Bioprinting of Small-Diameter Blood Vessels
نویسندگان
چکیده
منابع مشابه
Electrospun Fibrous Scaffolds for Small-Diameter Blood Vessels: A Review
Small-diameter blood vessels (SDBVs) are still a challenging task to prepare due to the occurrence of thrombosis formation, intimal hyperplasia, and aneurysmal dilation. Electrospinning technique, as a promising tissue engineering approach, can fabricate polymer fibrous scaffolds that satisfy requirements on the construction of extracellular matrix (ECM) of native blood vessel and promote the a...
متن کاملElectrospun Bilayered Vascular Scaffolds for Engineering Small Diameter Blood Vessels
336 ©2013 Society For Biomaterials
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We engineered implantable small-diameter blood vessels based on ovine smooth muscle and endothelial cells embedded in fibrin gels. Cylindrical tissue constructs remodeled the fibrin matrix and exhibited considerable reactivity in response to receptor- and nonreceptor-mediated vasoconstrictors and dilators. Aprotinin, a protease inhibitor of fibrinolysis, was added at varying concentrations and ...
متن کاملIn Situ Tissue Engineering of Functional Small-Diameter Blood Vessels by Host Circulating Cells Only.
Inflammation is a natural phase of the wound healing response, which can be harnessed for the in situ tissue engineering of small-diameter blood vessels using instructive, bioresorbable synthetic grafts. This process is dependent on colonization of the graft by host circulating cells and subsequent matrix formation. Typically, vascular regeneration in small animals is governed by transanastomot...
متن کاملElectrospinning collagen and elastin for tissue engineering small diameter blood vessels.
Nonwoven fibrous matrices of collagen and elastin have been prepared by means of electrospinning. Variations in the morphology of the scaffolds have been evaluated as a function of the ratio of the two proteins. Scaffolds having an architecture resembling the media of natural blood vessels have been obtained. Crosslinking has been used as a valuable method to improve the stability of such matri...
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ژورنال
عنوان ژورنال: Engineering
سال: 2020
ISSN: 2095-8099
DOI: 10.1016/j.eng.2020.03.019